Set in a quiet residential area, the Hotel Penzance provides views over Penzance harbour and bay. It is close to the town center, the Isles of Scilly ferry landing and the heliport. Nearby attractions include The Eden Project, Trust, National Maritime Museum, Cornish Seal Sanctuary and Minack Theatre.

All the 25 guest rooms are equipped with facilities such as satellite televisions, Internet connection, desks, daily newspapers and ironing facilities. They also have en-suite bathrooms with bath tub and hair dryer.

Set in a Mediterranean-style garden around an outdoor heated pool, the Hotel Penzance is a boutique-hotel converted from two Edwardian houses. It has a restaurant that serves modern European cuisine. Its on-site bar offers a selection of beverages including wines, cocktails and beers. Other amenities include a business center, wireless Internet access and meeting facilities.